The recurrent course of atopic dermatitis: therapeutic options for management of disease and prolongation of remissions

Atopic dermatitis is a common inflammatory skin disease, which most frequently occurred in children. The disease characterized as chronic, but only 20% of children have severe atopic dermatitis, while the other 80% achieve long-term remission by age 8. article summarizes main details about including statistical epidemiological data, signs course criteria for determining severity and aspects stepwise approach to therapy. authors paid special attention factors worsening dermatitis: role allergens provoking factors, secondary infection, drug hypersensitivity, concomitant diseases, breach dermatologist’s prescriptions. Despite large arsenal modern therapeutic methods, therapy long, persistent may not produce proper effect, this reason why acquires torpid course. Such clinical cases call finding new particular use Janus kinase inhibitors. In article, described case: 17-year-old patient K. complained widespread rashes on trunk accompanied intense itching; had been suffering from since early childhood, process recurrent character with alternating periods remissions exacerbations 2 times year. case describes successful inhibitor that was capable reduce signaling many cytokines contribute development symptoms relapsing who showed insufficient efficacy standard methods.